SSRIs: An Update
Scott Alexander revisits his stance on SSRIs, discussing new meta-analyses, broader trends in psychiatric medication efficacy, and potential explanations for the discrepancy between statistical and clinical observations.
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Scott Alexander revisits his stance on SSRIs, discussing new meta-analyses, broader trends in psychiatric medication efficacy, and potential explanations for the discrepancy between statistical and clinical observations.
Scott Alexander admits he was wrong about preschool programs like Head Start, discussing new evidence of their long-term benefits and considering the implications for understanding environmental effects and policy.
Scott Alexander shares his voting choices for California elections and ballot measures, offering brief explanations and occasional humor for each decision.
Scott Alexander investigates the complexities of using Google Trends for mental health research, proposing methods to improve accuracy and interpretation of search data.
A fictional account of an accidental AI creation that generates extremely controversial statements, leading to societal division and paranoia.
Scott Alexander explores the concept of people 'nominating themselves for the short end of a tradeoff' through their actions, and how this relates to ideas of desert and justice, sometimes conflicting with utilitarian calculations.
Scott explores how acetylcholine-related cognitive enhancers might work by increasing sensory precision and learning rate, while speculating on potential tradeoffs and acknowledging the highly speculative nature of these ideas.
Scott introduces a classified thread for advertisements, personals, and success stories, with uncertain frequency.
Scott Alexander examines a paper suggesting scientific progress is slowing relative to researcher numbers, arguing this trend is expected and potentially beneficial.
Scott Alexander uses the Jewish legend of the Chamber of Guf as a metaphor for subconscious thoughts, exploring its implications for behavior, OCD, and self-defeating thoughts.
Scott Alexander introduces an 'Anxiety Sampler Kit' for testing various anxiety supplements, aiming to personalize treatment and gather data through self-experimentation.
Scott Alexander analyzes a survey on readers' estimated probabilities of Kavanaugh's guilt, finding significant partisan differences and no clear consensus even with probabilistic thinking.
Scott Alexander shares a diverse collection of interesting links and news items, covering topics from historical anecdotes to recent scientific studies and cultural trends.
Scott Alexander uses a thought experiment about a drum-free town to explore libertarian ideas on community rights, then applies these concepts to real-world housing issues and proposes charter cities as a potential solution.
Scott Alexander reports on a survey about nighttime ventilation interventions, finding modest overall improvements but some individual success stories.
Scott Alexander highlights diverse comments on the NIMBY debate, exploring contrasting views on urban living and various aspects of urban development.
Scott Alexander presents counterarguments to YIMBY housing policies, questioning their effectiveness and considering NIMBY perspectives.
Scott Alexander announces winners of the adversarial collaboration contest and shares participant feedback, while reflecting on potential issues with the format.
The post explores how correlated variables can diverge at extreme values, applying this concept to happiness measures and moral systems.
The post examines the theory of treating schizophrenia's prodrome stage, exploring how early intervention might prevent full-blown schizophrenia and discussing the biological mechanisms behind the disease's progression.
Scott reviews 'The Black Swan' by Nassim Taleb, examining its key concepts and Taleb's unique perspective on probability and risk.
Scott Alexander uses the evolution of genetic science as a metaphor to explore how other fields might benefit from recognizing the polycausal nature of complex phenomena.
This Adversarial Collaboration Contest entry examines the evidence and debates surrounding transgender children transitioning, covering desistence rates, social transitioning, puberty blockers, and mental health outcomes.
This collaboration examines mandatory vaccination policies and potential vaccine harms, concluding mandates are likely unnecessary and vaccines remain important for public health despite some ongoing safety concerns.
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