Some Antibiotic Stagnation
Scott Alexander debunks a misleading graph on antibiotic discovery and presents more accurate data, discussing reasons for the decline in antibiotic development.
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Scott Alexander debunks a misleading graph on antibiotic discovery and presents more accurate data, discussing reasons for the decline in antibiotic development.
Scott Alexander clarifies that his blog Slate Star Codex is not strictly representative of the rationalist community, and addresses common misconceptions about the blog's relationship to rationalism and effective altruism.
Scott criticizes a NYT article on sugar industry influence, arguing that such bias is common across food industries and doesn't justify completely reversing nutritional advice.
Scott Alexander argues against harshly criticizing various groups often mocked by both left and right, emphasizing nuanced thinking and engagement with evidence.
Scott Alexander responds to critiques of his Anti-Reactionary FAQ, addressing focus on recent trends, class gaps, sexual norms, equality, tone, and the concept of the Cathedral.
Scott Alexander reviews 'The Anti-Racialist Q&A', praising its approach to arguing against racism and its display of epistemic virtue.
Scott Alexander examines a theory linking autism and schizophrenia to human self-domestication, initially dismissing it before reconsidering its merits in light of Williams Syndrome.
A fictional account of an accidental AI creation that generates extremely controversial statements, leading to societal division and paranoia.
An open thread post covering comment highlights, potential comment policy changes, user unbanning, and guidelines for reader communication with the author.
Scott Alexander reviews analyses of various UBI plans, finding most unrealistic, then speculates on alternative approaches to implement UBI successfully.
Scott Alexander endorses Clinton (or Johnson/Stein in safe states) over Trump, citing concerns about Trump's unpredictability and potential negative impacts on conservatism and social dynamics.
Scott Alexander humorously explores the World Cup's complex rules, game theory in soccer, and unusual incentive structures in international tournaments.
Scott Alexander gives a satirical graduation speech questioning the value of formal education and proposing an alternative basic income system, emphasizing kindness and epistemic humility.
Scott Alexander delivers a wedding speech for Mike and Hannah Blume, blending personal anecdotes, humor, and reflections on the couple's potential impact on future generations.
Scott analyzes a new survey of AI researchers, showing diverse opinions on AI timelines and risks, with many acknowledging potential dangers but few prioritizing safety research.
Scott Alexander examines a failed replication of a study claiming analytical thinking promotes religious disbelief, and discusses the broader implications for understanding the relationship between thinking styles and religious belief.
Scott Alexander discusses a study challenging the idea that childhood abuse lowers IQ, and explores its implications for understanding the effects of child abuse on various outcomes.
Scott Alexander critically examines a major meta-analysis on antidepressant efficacy, noting potential biases and comparing its surprising drug rankings to his own previous analysis.
Scott Alexander reviews a paper that claims to solve the Fermi Paradox by using probability distributions instead of point estimates in Drake Equation calculations.
A study on expert prediction of behavioral economics experiments finds that experts have only a slight advantage over non-experts, suggesting that a separate 'rationality' skill may be more important than specific expertise.
Scott reviews a paper proposing a computational model of mood and emotions based on predictive processing, discussing its implications for understanding mood disorders.
Scott Alexander analyzes a study suggesting cloth masks may be harmful, but remains cautiously in favor of their use despite the uncertainty.
The post explores a new model for understanding mental disorders as networks of interconnected symptoms rather than discrete diseases with underlying causes.
Scott reviews a paper proposing that psychedelics work by relaxing priors in the brain, potentially treating mental illness but also risking side effects.
Scott reviews a theory about serotonin receptors that explains how they help cope with stress, and discusses its implications and limitations.